How To Prevent Skype from Crashing on Startup

Is Skype crashing on start-up? Here is a quick resolution that seems to work almost all the time in Windows:

1. If the Skype icon is displayed in the system tray at the bottom right of the screen, right-click it and select Quit.
2. Click Start, type "run" and press Enter. (On Windows XP: Click Start and then Run.)
3. Type "%appdata%\skype" and click OK.
4. Locate and delete the file shared.xml. The file may be displayed as shared if file extensions are not displayed by default on your computer.
5. If you cannot find this file:
6. Click Start, type "run" and press Enter. (On Windows XP: Click Start and then Run.)
7. Type "control folders" and click OK.
8. In the View tab, ensure that Show hidden files and folders is enabled.
9. Repeat the instructions from the beginning.
10. Restart Skype.

Provided by Skype Crashes on Startup Windows 7 - Skype Community

Crashing problem may occur due to corrupt registry entries and junk files in the computer.... you can fix it using Reg In Out System Utilities...!
Best of Luck..!

My humble advise would to stay away from Registry Cleaners