Setting of the ACLs for the root directory of a logical partition where the users profiles are saved

HI

I have Windows 7 SP1 and I should only move the users profiles (without the default profile) and the public folder in a NTFS logical partition.

I should modify the ACLs of the root directory (\) of the logical partition to still have a coherent and stable system or not? If so, how should I modify these ACLs?

THANKS

BYE