Re: Help Windows for applications popping up.
Usually, I'd ask if you have the option to check some "don't show again" checkbox, but if you say that the help window doesn't close, I assume it's more serious.
Are you SURE that F1 is not stuck? Maybe something spilled on the keyboard and is making a short circuit inside. Try using a different keyboard for a while to rule out a keyboard problem.
Many factors can be at fault here. I'd also check about scanning for adware\viruses\spyware etc...
You can try to disable the "Help and Support" service from Windows services and see if that helps.
Do you have any 3rd party software that takes over your keyboard or creates hot-keys or keyloggers installed?
Here's some more info:
Windows Help and Support keeps popping up. - Microsoft Answers
Operating System Windows 7 Ultimate x64
Computer Type Desktop
OS Service Pack SP1
Internet Explorer Version 9
CPU Type and Speed Intel Core i7 920 2.67GHz Hyper-threaded(8)
Motherboard Chipset Gigabyte Technology Co., Ltd. EX58-EXTREME
System BIOS Revision F13
System Memory Type Kingston
Video Card Type and Speed NVIDIA GeForce 9800 GT
Computer Monitor 3 X LG W2486 24.0"
Sound Card Realtek HD
Speakers Creative
Headset/Microphone Sennheiser
Hard Drive 40 TB
Optical Drives 2 X PIONEER BD-RW BDR-205 SCSI
Modem-Router Type Microsoft
Network Adapter Realtek
Anti-virus Software Nod32
Computer Skill Level Self-Taught Expert
Windows Experience Index 5.9
Favorite Application My personal created ones!